What Water is this Water? Huh?

Purified Water: 

• Water, usually produced using Groundwater or Tap water, then filtered or processed to remove impurities and contaminants, including : chemicals, micro-organisms (microbes, fungi…), metals (copper, load…).
• In most Western countries, Public Drinking Water is purified to make it safe for human consumption.
• It is produced in a range of purities, as standards for drinking water around the world vary. 

Mineral Water: 

• Is a Purified Water produced using water from a Mineral Spring that contains various minerals, such as salts and sulfur compounds. Mineral water may usually be still or sparkling according to the presence or absence of added gases. 

Distilled Water: 

• Is a Type of Purified Water taken to the extreme end of purity.
• Common use for distilled water is in batteries and CPAP humidifiers
• Distillation involves boiling water and collecting the steam, which returns to water upon cooling.
• It is usually considered sterile, depending on the collection of the steam and water.
• Distilled water is made to get you as close to pure H2O as possible : no minerals, no chemicals, no microorganisms, no impurities.
• It is Hypotonic with an Osmolarity of zero mOsmol/L
• While distilled water is the purest type of water, it’s not necessarily the healthiest for everyone :
Distillation typically removes around 99.9% of all minerals found in tap water. It is true that tap water is not a major source of mineral intake for most people, and drinking distilled water should be relatively safe, ONLY as long as a well-balanced diet is followed. In fact, exclusive distilled water drinking habits can be associated with : nausea, headache, vertigo, increased risk of fracture, preterm birth, heart disease ,loss of memory, dementia and Coma. 

Sterile Water: 

• Is a quality of Purified Water or Distilled Water that contains NO viable (able to reproduce) microorganism, such as fungi, spores, or bacteria.
• Homemade Sterile Water made by boiling the water in a pot for 20 minutes or more will kill most pathogen microorganisms; it would however not be classified as Sterile Water for Medical Purposes.
• Sterile Water belongs to a class of drugs called Sterile Irrigating Solutions.
• Contains water that is sterilized and packaged for use as an irrigant.
• By respecting certain criteria during manufacturing process, it can be adapted for injection
• No antimicrobial agent or other substance has been added.
• “In use” time, after first entry, is 4-6h in ISO 5 environment at room temperature 

Sterile Water for Irrigation, USP: 

• Is a sterile, distilled, nonpyrogenic water intended only for sterile irrigation, washing, rinsing and dilution purposes. It does not pass the same UPS regulation standards as SW for injection
NOT SAFE FOR INJECTION

Sterile Water for Injection, USP: 

• Is a sterile, distilled, nonpyrogenic water intended for injection,
• It is chemically designated H2O. pH 5.0 to 7.0.
• It contains no bacteriostat, antimicrobial agent or added buffer,
• It is supplied only in single-dose containers
• Used for : dilute (concentrated solutes) or dissolve (powdered drugs) for injection.
NOT safe for injection without a solute (may result in hemolysis). 

Bacteriostatic water for injection, USP: 

• Is a sterile, distilled, hypotonic, nonpyrogenic water intended for injection, that contains a Preservative with Bacteriostatic activity
• Can be used multiple times up to 28 days once opened,
• It should be stored in a dark place at temperatures between 15 to 25 degrees Celsius
• Depending on multiple factors (including concentration, pH, temperature), the preservative used can :
• Inhibit growth of newly contaminating microorganisms (Bacteriostatic)
• OR destruct existing microorganisms (Antimicrobial)
• Most antimicrobial are used in Sterile Water for their Bacteriostatic properties
• Many preservatives with Bacteriostatic activity can be used
• Most common Antibacterial preservative for injection is Benzyl alcohol
• Most commonly used Antifungal preservative is a combination of Methylparaben and propylparaben
• The key criteria for antimicrobial preservative selection are the preservative's dose, antimicrobial functionality, and “effect on the active ingredient”.
That means, it may be NOT adapted to the product or solute you are intending to use it with (Please check before use : Medicinal leaflet , Doctor, Pharmacist, Medical Supplier)

Sterile Saline for Injection 0,9%: 

• Is a sterile, distilled, nonpyrogenic water intended for injection, that contains 9 grams of NaCl salt for each 100 ml of Sterile Water for injection.
• Meant to be isotonic to human Blood (ready for injection).

Other Sterile water preparations for injection: 

• Depending on pH, osmolarity, the chemical or mineral used, the resulting product can be ready for injection, suited for injection (used to dilute or dissolve several drugs).
• However, you must seek professional advice as there are risks of : Infusion site reaction, vein thrombosis, deactivation or precipitation of drugs, and creation of toxic or pro-allergic (causing allergic reaction) components.